Dreamscaping

Dreamscaping is the art of JeeYoung Lee, a South Korean artist who spends weeks, or even months, transforming her 3m x 6m studio into whatever land her imagination dictates...


Sweet Appetite
Treasure Hunting

JeeYoung stars in each landscape, often becoming one of the creatures she creates. 

Birthday
Resurrection 

Whilst some of her work is enchanting and delicate, sometimes it is jarring and vivid. 

Blackbirds
Food Chain
Flu

In 'Panic Room' she plays with perspective to create surrealism. 

Panic Room

I am totally enamoured with her. Every dreamscape she creates is magical and it shows what you can create with such a small space.

Gamer
I'll Be Back

If you want to see more of her work, you can see the full exhibition on-line, or head down to the OPIOM gallery (Opio, France) this time next where her work will be going on display for a month. 

Larry is that you?

So the phrase as happy as Larry, the namesake for this blog, has left a lot of people wondering who Larry is. I think it might be this guy...


Pointless Excellence

Sometimes it's nice to spend a little time on something without too much real world significance. Here are some of my favourite, very pointless, very excellent ways to 
spend half an hour. 


Scribbler Too allows creates interconnecting lines 
between your doodles, to create beautiful web-like art. 

Use your ears to locate the invisible cow. Simple.



Make abstract Picasso-esque portraits.



Meditation Flowers
Sing to your flowers and see what happens.




Enjoy!

Stem Cells : What are they and why are they so awesome?


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'Stem cells' are talked about a lot, but what really are they?


Stem cells are unspecialised cells, capable of making the specialised cells that make up our body. At conception, just after fusion of sperm and egg, we exist as one cell. This cell divides in to 2 daughter cells, which in turn divide to become 4 cells, which become 8, 16, 32, 64 and so on, until we have a LOT of cells. But our cells aren't all the same - our arms are pretty different to our eyes! Why? Our cells differ from one another according to the particular proteins, such as growth factors, that they are exposed to during development. The type and quantity of these proteins defines the cell fate. Cells exposed to lots of 'Growth Factor A' and a little bit of 'Growth Factor B' become liver cells. Nearby cells which are exposed to less of 'Growth Factor A' and more of 'Growth Factor B' become pancreas cells. It's a little more complicated than that, but you get the picture. It's about gradients. The proteins are responsible for switching certain genes on and off. So even though our cells contain the same genes, the active genes are different. This is why there are very distinct differences between pancreas and liver, arm and eye. This process affects what we call the potency of cells. 

We begin as just one cell, capable of making every possible cell in our body. As this cell divides and develops, the variety of possibilities for what these daughter cells could become reduces. We refer to this as potency. Totipotent cells are able to differentiate into all possible cell types, pluripotent cells are able to differentiate into almost all cell types, multipotent cells are able to differentiate into a particular family of cells... and so it continues, until we are left with differentiated cells, such as our skin cells, which can only be themselves. This transition from totipotent cells to differentiated cells is one-way; it doesn't reverse. A key feature of stem cells is that, as well as producing differentiated daughter cells, they can produce more of themselves. This means that they can replenish the pool of stem cells available. 

So why are they so exciting?



Babies have high populations of stem cells, which is why they are capable of incredible feats such as RE-GROWING FINGERS! The stem cells near the wound are able to divide and differente into the cells required to rebuild the finger. You can kind of think of them as an emergency response team, capable of rebuilding our bodies. As adults, we still have some stem cell populations in our body, which regenerate and replenish tissues. For example, our bone marrow contains stem cells capable of making bone, fat, cartilage and muscle cells for us. 

For a long time we have been extracting stem cells, either from embryos (which throws up a whole realm of ethical issues) or from adults. We can then do two pretty cool things with them. 
  1. We can harvest particular stem cells from donors and transplant them into patients with life-threatening diseases, to replenish tissues. (This process is difficult and limited.)

  2. We can, in theory, take stem cells and artificially induce the process of differentiation. Put simply, we could turn a stem cell in to any type of cell that we want. We could create cells of the eye or brain, insulin-producing cells, heart valves, you name it. These could be transplanted back in to compatible patients. We could cure blindness, Parkinsons, Alzheimers, diabetes, spinal chord injury, strokes and so much more. 
There are currently stem-cell trials underway for some conditions such as multiple sclerosis and degenerative eye diseases. It is important to realise that the transition from theory to reality can take decades, at least. But there may come a time when paralysis and some of these diseases are a thing of the past.

In theory, we can pretty much do anything with stem cells. Unfortunately reality throws a whole load of issues in the way to make things a little harder. But recently a few things have changed. Firstly we are learning more and more about development and using this knowledge to get better at differentiating cells in the lab. Secondly and VERY excitingly, a Japanese scientist, Shinya Yamanaka, was able to reverse the direction of development. He took a differentiated adult cell and changed which genes were switched on and off, turning it back in to a pluripotent stem cell. Or at least a cell that looks and acts an awful lot like a pluripotent stem cell. We call these induced pluripotent stem cells, or iPSCs. The science is still young, but just think... one day a person diagnosed with a degenerative brain disease could go to the doctor and undergo a harmless procedure to harvest some cells. These cells could be taken to the lab, turned in to IPSCs and then transformed into specialised healthy brain cells to be transplanted back in to the patient. Disease cured. No risk of rejection as the cells came from the patient. 

Another VERY exciting, VERY awesome advance in technology is 3D printing. Utilising stem cells for 3D printing could have some very exciting results. Imagine for a second, that instead of using different colours of ink, these printers used living ink - made up of different types of cell. In fact, you don't need to imagine, just watch this video...



This is only the beginning. We are now successfully printing windpipes and attempts are underway to print human organs. If you have 17 minutes, I recommend Anthony Atala's TED talk on printing a human kidney. His team are pioneers of tissue engineering and organ printing. 

I hope this has got you excited about regenerative medicine. I cannot wait to see what incredible advances there are over the next few decades. Stem cell treatments and regenerative medicine are just some examples of awe-inspiring scientific discoveries and their modern applications. So please share and spread the knowledge. By getting more people aware and excited about science, we can get more funding directed to these areas and inspire more bright young minds, from all backgrounds, to pursue science. 

If you have any questions or want to know more, feel free to comment below. 

Turtle Soldier


Travel Favourites: Bolivia

I am a travel fanatic; I find travelling to be one of the most wonderful, happiness-inducing experiences out there. As such, I think Happier Than Larry deserves a travel section. At last count I had made it to 30 countries, so I thought it was time to share some of my top places. I'd love to hear some of your favourite spots and incorporate them into a future trip, so please feel free to comment with any of your recommendations. In the meantime I hope my Travel Favourites feature gives you some inspiration or nostalgia for adventures of your own. 

Bolivia on World Map
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Bolivia is easily one of my favourite countries. With a breathtaking array of natural wonders and rich indigenous culture, it is easily a place to fall in love with. Much poorer and less industrialised than some of its more European neighbours, Bolivia has a humble vibe and offers a slightly slower pace of life. Major ethnic groups are broadly divided by the altitude, between the higher, colder mountainous Altiplanos region and the lower warmer regions. There are many subcultures and ethnic groups, as well as populations of Europeans, mestizos of mixed euro-indigenous descent and afro-Bolivians. Unlike in some parts of the world, you feel that the indigenous cultures are very much alive and present and not a thing of the past. This is visible in the rituals, customs, music and dress, which are utterly captivating.

Celebrating the sunrise on winter solstice in Tiwanaku. Source: Makanaka

La Paz from above

La Paz , is a chaotic, sensory overload of a city, which takes up every perceivable inch of land in the valley it occupies. 
At 3600+ metres above sea level, you can expect to feel somewhat incompetent during any physical excersion until your red blood cell count increases after a month or so. This is particularly poignant when you're being quite significantly overtaken by people in their 70s and 80s whilst walking uphill!
Spice Markets. Source: Trekearth
La Paz is an abbreviation of Nuestra Señora de La Paz, which translates to 'our lady of peace'. There are many peaceful elements to the city, but they are juxtaposed against the loud traffic and the hustle and bustle. You can absorb some of the countries history and culture exploring the museums or witches markets or venture off to trek the local mountains or ruins. The city offers vibrant fabrics, gorgeous wool clothing, rich herbs and spices, llama foetuses and strips of technology shops; it's a real mix!


Source: Too Grey To Grind
For the adrenaline junkies, 'The World's Most Dangerous Road' is one hell of a ride. You can cycle down the perilous trail. Starting up at nearly 5000m, where the altitude hits you, you are surrounded by frozen lakes and llamas with icycles in their fur. As you descend, it gradually becomes warmer, you cycle down through the clouds and waterfalls and are faced with a perilous drop, hundreds of metres down to the jungle below. After an exhilarating several-hour descent, you end up down in the jungle, with a tropical climate and the sounds of birds and monkeys around you. You can take the safer road back to La Paz, or recuperate in the jungle for a couple of days.

There are many other interesting cities and towns across the country, including Sucre: the whitewash sugar cube style capital, Oruro: a truly incredible place to celebrate carnival, and some striking mining towns.  However I think what really makes Bolivia special, is the range of natural beauty at your fingertips. Salar de Uyuni, the worlds largest salt flat, is perhaps the most awe-inspiring place I've ever been. It was formed as an ancient salt lake when the Nazca and South American continents colided, forming the Andes mountain range. The lake has long since dried out, leaving beautiful, geometric salt formations for miles. 

Jeeps on the salt flats
Sunset on the salt flats, copyright Ian Parker














If you visit when there is a little rain on the salt, the surface perfectly reflects the sky and it's as if you are walking in the clouds. It feels truly magical. 


Thunder over the salt flats, copyright Ian Parker

Pink dolphins. Source: Andes Discovery
One of the other great natural beauties of Bolivia is the Amazon Basin; home of elusive jaguars, crocodiles, alligators, piranha, anaconda, capybara, monkeys and a plethora of weird and wonderful creepy crawlies. A lesser known occupant of the Bolivian Amazon is the Amazon river dolphin. If you can brave the parasite and alligator infested waters, you can swim with these playful, pink (!!) dolphins. On hindsight, like The World's Most Dangerous Road, this sounds like a terrible idea, but it is seriously fun as well! 

There is so much more to mention, not least lake Titicaca with its floating islands that people live on. I've spent a couple of months in Bolivia and still feel like there is so much more to see. I cannot recommend it enough. Also it is insanely cheap, so you can do all of these incredible activities without breaking the bank. 

Bolivia is a country not without its struggles (socio-political and economic), so if you are there, try to travel responsibly, reinvest money into the local communities and perhaps get involved with some community projects. (You may have heard me raving about the CMA - a charity providing prosthetics to low-income Bolivian amputees.) 

Happy travels everyone! 

Incredibox



Incredibox is one of my favourite sites out there. It's a drag and drop beat-making program that provides hours of entertainment, regardless of your musical talent level. After a few minutes of playing, you may stumble stumble across previously unexplored genres; eclectic robofunk or minimalist native-american electro. Our friend Jenni somehow manages to make these ethereal, stripped-back, James Black-esque sounds every time. Mine are a little less distinguished! 

If you have a few minutes, I seriously recommend it. 

You're The Apple Of My Owl

apple of my owl

Franny Zywicki via AnOther

Hand Art: A Canvas At Your Fingertips

Guide Danielle ditches the more conventional canvases, favouring human hands. His work has me yearning to fingerpaint. 

Hyper-realistic Handart
Hyper-realistic Handart
Hyper-realistic Handart
pesce_tropicale  chimpanzee
Hyper-realistic Handart
Handart-zeebra
Handart-teapots
Pretty breathtaking huh?
Via Pikchur

Cooking Like You've Never Seen It

Here's a new take on a favourite dip, by Academy Award Nominee animator PES. His animations are some of the most satisfying things I've ever watched. 



If you're in the mood for spaghetti... 

Learning Something New Everyday: Free Education

You really can learn something new everyday...

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The internet is a treasure trove of information, that can teach us so much more than how to bread a cat and what Nicholas Cage looks like as various Disney princesses. No disrespect to breaded cats or Disnefied Nicholas Cage - both are highly entertaining - but free education is a wonderful thing and as UK Higher Education fees continues to skyrocket, it is encouraging to see the increase in free, high-quality online education. The range of courses available is incredibly diverse and includes some very high standard teaching; a professor of mine at Bath, a leading cancer researcher and lecturer, offers a free online course in the genetics of cancer. It seems that regardless of your schedule, or interests, there is something for you, be it sustainability, cryptographyhow to read a mind, climate change, drugs and the braina new language, social psychology, business strategy or how to train your dragon

Some of the best sites I've come across are Future Learn, Coursera and Alison, but there are hundreds out there. So if you have a few hours to spare and want to learn something new, why not have a browse and get inspired? Personally I want to learn another language this year, do some coding and get better at upcycling :)

Thread Installations by Gabriel Dawe

These incredible installations are the work of Gabriel Dawe who 
simply uses coloured thread to play with light and create these enticing prisms.


  Somehow I think this wouldn't work so well if I tried it at home,  but I'm tempted to try...

Sir David Attenborough vs The Fresh Prince

Sir David Attenborough did an AMA (ask me anything) on Reddit recently which led to this beautiful amalgamation of two of the best things ever. 


Via IFLS


























See the full AMA here

People Are Awesome 2013 - 2014

You'll find a lot of videos by this title on YouTube, which showcase the most incredible, adrenaline-fueled human feats. They are well worth checking out. 
Disclaimer: They may inspire you to do really stupid stuff...

Animal Prosthetics

I love seeing technology put to good use. Here are some beautiful examples of human ingenuity being used to help out our animal friends. 


   Mosha the elephant

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   Beauty the eagle
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   Winter the dolphin
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   Mr Stubbs the alligator
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   Cassidy the dog

Cassidy the dog walks to the beach with her owner.
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If you are interested in prosthetics, I've been working for a couple of years with a Bolivian organisation that provides prosthetic limbs to people who can't afford healthcare. You can learn more on our website or like us on facebook. We have lots of no-fee volunteer positions in one of the most beautiful countries in the world, so if you fancy an extended holiday or a career break, why not get involved?

Non-Conformism


Darwin Deez

The perfect music video. 



Home Inspiration

Now and then people take home design to a whole new level. 
Here are some of my absolute favourites from around the world that I hope to draw inspiration from in my own dream home one day. 


1. A musical wall
Nothing puts a silver lining on a rain-cloud like this beauty that plays you a song when it rains. 

Source: Ingeniumetars









































2. Staircase slides
Simply awesome. No more grumpy mornings. 

stairs with slides
Source: Twisted Sifter




























3. A River Cocoon
The perfect place to read. Not entirely sure how you make it in there with a dry book though...

bed, decor, hammock, hanging, interior, lake - inspiring picture on Favim.com
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4. Moss graffiti
Perhaps a slightly more attainable dream right now, this mix combines moss, buttermilk and sugar to make paint-on living graffitt
















5. A Bedroom Pool 
Because why wouldn't you want a pool in your bedroom?
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